SML1263

Arylquin 1

≥98% (HPLC)

• 同義詞: 3-(2-Fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine)
• 經驗公式（希爾表示法）: C₁₇H₁₆FN₃
• CAS號碼: 1630743-73-5
• 分子量：: 281.33
• MDL號碼: MFCD28580129
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825755
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: , white to yellow to light brown
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F
• InChI: 1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20)
• InChI 密鑰: RHAQINSYYSNKKI-UHFFFAOYSA-N

描述

生化／生理作用

Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable