推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 10 mg/mL, clear
儲存溫度
2-8°C
InChI
1S/C20H21F3N4O/c21-20(22,23)15-5-7-16(8-6-15)26-12-9-25(10-13-26)11-14-27-18-4-2-1-3-17(18)24-19(27)28/h1-8H,9-14H2,(H,24,28)
InChI 密鑰
CCIZQGRSEAHATK-UHFFFAOYSA-N
生化／生理作用
氟班色林是 5-HT1A 受体激动剂和 5-HT2A 受体拮抗剂。氟班色林对人 5-HT1A受体 (Ki = 1 nm) 具有高亲和力，对 5-HT2A (Ki = 49 nm) 和 D4 (Ki = 4–24 nm) 受体亲和力较低，对多种其他神经递质受体和离子通道的亲和力可忽略不计。氟班色林被用作女性绝经前性欲减退 (HSDD) 的一种新型非激素治疗方法。氟班色林。最近，在帕金森氏病模型中发现氟班色林可减轻 L-DOPA 引起的运动障碍。
特點和優勢
这种化合物是神经科学研究的特色产品。点击此处发现更多特色神经科学产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Drug for low sexual desire carries significant harms, FDA advisers find.
Ray Moynihan
BMJ (Clinical research ed.), 341, c3339-c3339 (2010-07-09)
John Thorp et al.
The journal of sexual medicine, 9(3), 793-804 (2012-01-14)
Hypoactive Sexual Desire Disorder (HSDD) is characterized by low sexual desire that causes marked distress or interpersonal difficulty. To assess the efficacy and tolerability of flibanserin, a postsynaptic 5-HT1A agonist/5-HT2A antagonist, in the treatment of premenopausal women with HSDD. North
Boehringer Ingelheim withdraws libido drug for women.
Jeanne Lenzer
BMJ (Clinical research ed.), 341, c5701-c5701 (2010-10-14)
Dysfunctional women remain unsexed.
Michael G Wyllie
BJU international, 106(3), 431-432 (2010-07-27)
Leonard R Derogatis et al.
The journal of sexual medicine, 9(4), 1074-1085 (2012-01-18)
Hypoactive sexual desire disorder (HSDD) is the most common form of female sexual dysfunction and is characterized by low sexual desire that causes distress. The aim of this study was to assess the efficacy and safety of flibanserin, a postsynaptic
文章
DISCOVER Bioactive Small Molecules for Neuroscience
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