SML0452

AZ513

≥98% (HPLC)

• 同義詞: 2,3-Dichloro-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide
• 經驗公式（希爾表示法）: C₁₄H₉Cl₂N₃O
• CAS號碼: 1335231-15-6
• 分子量：: 306.15
• MDL號碼: MFCD22666398
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329824731
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 15 mg/mL (clear solution)
• 儲存溫度: 2-8°C
• SMILES 字串: Clc1cccc(C(=O)Nc2cnc3[nH]ccc3c2)c1Cl
• InChI: 1S/C14H9Cl2N3O/c15-11-3-1-2-10(12(11)16)14(20)19-9-6-8-4-5-17-13(8)18-7-9/h1-7H,(H,17,18)(H,19,20)
• InChI 密鑰: SIMLBFHHXAMGGM-UHFFFAOYSA-N

描述

生化／生理作用

AZ513 is a reversible, noncompetitive FAAH inhibitor.

AZ513 is a reversible, noncompetitive FAAH inhibitor. It also binds non-competitively at a site distinct from the catalytic site. AZ513 is 20-fold more potent against rat FAAH (IC₅₀ 27 nM) than the human form (IC₅₀ 551 nM).

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable