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Merck
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Key Documents

SCP0171

Sigma-Aldrich

Interleukin 1b Converting Enzyme Substrate

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About This Item

經驗公式(希爾表示法):
C29H36N6O10
分子量::
628.63
分類程式碼代碼:
12352200
NACRES:
NA.32

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥75%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Ac-Tyr-Val-Ala-Asp-pNA

應用

Ac-YVAD-pNa (acetyl-Tyr-Val-Ala-Asp-p-nitroanalide) is a selective chromogenic substrate for the detection of Interleukin-1b Converting Enzyme/caspase 1.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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C Bossenmeyer-Pourié et al.
Neuroscience, 95(4), 1157-1165 (2000-02-22)
To further explore the contribution of caspase-1/interleukin-1beta-convening enzyme in the consequences of hypoxia in developing brain neurons, its temporal expression profile was analysed by immunohistochemistry and western blotting in cultured neurons from the embryonic rat forebrain subjected to a hypoxic
Ori Nov et al.
Endocrinology, 151(9), 4247-4256 (2010-07-28)
Central obesity is frequently associated with adipose tissue inflammation and hepatic insulin resistance. To identify potential individual mediators in this process, we used in vitro systems and assessed if insulin resistance in liver cells could be induced by secreted products
Natasha Ann Pereira et al.
Biochemical and biophysical research communications, 377(3), 873-877 (2008-11-04)
Many designated substrates and inhibitors have been widely used to investigate the roles of caspases in apoptotic death during mammalian cell culture. However, the specificities of these substrates and inhibitors have not been systematically evaluated. As a result, conclusions on

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