SAB5702998

Anti-UPF1/RENT1 Antibody, clone 5D5C4, Rabbit Monoclonal

• 同義詞: HUPF1, NORF1, RENT1, pNORF1, smg-2
• 分類程式碼代碼: 12352203
• NACRES: NA.46

屬性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 5D5C4, monoclonal
• 形狀: liquid
• 分子量: 140 kDa
• 物種活性: rat, human, rat
• 濃度: 0.4mg/ml
• 技術: immunofluorescence: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGPGGGGAGGPGGAGAGAAAGQLDAQVGPEGILQNGAVDDSVAKTSQLL
• UniProt登錄號: Q92900
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... UPF1(5976)

描述

一般說明

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UPF1/RENT1 (Q92900).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB,IF/ICC, IP

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1