SAB5702738

Anti-LIN28A Antibody, clone 2S1I10, Rabbit Monoclonal

• 同義詞: CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A
• 分類程式碼代碼: 12352203
• NACRES: NA.46

屬性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 2S1I10, monoclonal
• 形狀: liquid
• 分子量: 26 kDa
• 物種活性: human, rat, rat
• 濃度: 0.70 mg/mL
• 技術: immunofluorescence: 1:50 - 1:200; western blot: 1:10000 - 1:20000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKS
• UniProt登錄號: Q9H9Z2
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... LIN28A(79727)

描述

一般說明

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IF/ICC

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1