SAB5702381

Anti-BMP6 Antibody, clone 6N5S9, Rabbit Monoclonal

• 同義詞: VGR, VGR1
• 分類程式碼代碼: 12352203
• NACRES: NA.46

屬性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 6N5S9, monoclonal
• 形狀: liquid
• 分子量: 42 kDa
• 物種活性: rat, rat, human
• 濃度: 0.50 mg/mL
• 技術: immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: DGPYDKQPFMVAFFKVSEVHVRTTRSASSRRRQQSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLN
• UniProt登錄號: P22004
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BMP6(654)

描述

一般說明

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human BMP6 (P22004).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IF/ICC

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1