SAB5702009

Anti-PKC alpha Antibody, clone 1G10S8, Rabbit Monoclonal

• 同義詞: PRKCA,AAG6,PKC-alpha,PKCA,PRKACA,PKC alpha
• 分類程式碼代碼: 12352203
• NACRES: NA.46

屬性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 1G10S8, monoclonal
• 形狀: liquid
• 分子量: 76 kDa
• 物種活性: rat, human, rat
• 濃度: 0.26 mg/mL
• 技術: immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: MTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV
• UniProt登錄號: P17252
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... PRKCA(5578)

描述

一般說明

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 573-672 of human PKC alpha (P17252).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC, IP

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1