SAB5702005

Anti-Bak Antibody, clone 7Q3T8, Rabbit Monoclonal

• 同義詞: BAK1,BAK,BAK-LIKE,BCL2L7
• 分類程式碼代碼: 12352203
• NACRES: NA.46

屬性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 7Q3T8, monoclonal
• 形狀: liquid
• 分子量: 25 kDa
• 物種活性: mouse, mouse
• 濃度: 0.089 mg/mL
• 技術: immunohistochemistry: 1:50 - 1:100; western blot: 1:500 - 1:2000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: RQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIG
• UniProt登錄號: Q16611
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BAK1(578)

描述

一般說明

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

免疫原

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Recombinant fusion protein containing a sequence corresponding to amino acids 11-82 of human Bak (NP_001179.1).

應用

WB, IHC

安全資訊

• 象形圖: GHS07,GHS09
• 訊號詞: Warning
• 危險聲明: H317,H411
• 防範說明: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危險分類: Aquatic Chronic 2 - Skin Sens. 1
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3