SAB5701783

Anti-Phospho-JNK1/2/3-T183/T183/T221 antibody produced in rabbit

• 分類程式碼代碼: 12352203
• NACRES: NA.43

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體產品種類: primary antibodies
• 無性繁殖: monoclonal
• 形狀: liquid
• 物種活性: mouse, human, rat
• 濃度: 1.61 mg/mL
• 技術: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt登錄號: P45983/P45984/P53779
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pThr183/pThr183/pThr221)

描述

一般說明

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]

免疫原

A phospho specific peptide corresponding to residues surrounding T183/T183/T221 of human JNK1/2/3

外觀

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable