SAB5700324

Anti-Phospho-Rb-S811 antibody produced in rabbit

• 同義詞: OSRC, PPP1R130, RB, RB1, Rb, p105-Rb, pRb, pp110
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 106
• 物種活性: human
• 濃度: 0.55 mg/ml
• 技術: immunofluorescence: 1:50-1:100; western blot: 1:1000-1:2000
• UniProt登錄號: P06400
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pSer811)
• 基因資訊: human ... RB1(5925)

描述

一般說明

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

免疫原

A synthetic phosphorylated peptide around S811 of human Rb (NP_000312.2).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable