SAB4702105

Monoclonal Anti-CD200 PE produced in mouse

• 同義詞: MOX, MRC, OX-2
• 分類程式碼代碼: 12352203

屬性

• 共軛: phycoerythrin (R-PE) conjugate
• 品質等級: 100
• 抗體產品種類: primary antibodies
• 無性繁殖: OX-104, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: flow cytometry: suitable
• 同型: IgG1κ
• UniProt登錄號: P41217
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CD200(4345)

描述

一般說明

CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.

特異性

The mouse monoclonal antibody OX-104 recognizes an extracellular epitope of CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.

免疫原

recombinant human CD200

外觀

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

準備報告

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

儲存和穩定性

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

其他說明

The antibody solution should be gently mixed before use.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable