SAB4702066

Monoclonal Anti-CD138 PE produced in mouse

• 同義詞: SDC, SYND1, syndecan 1
• 分類程式碼代碼: 12352203

屬性

• 共軛: phycoerythrin (R-PE) conjugate
• 品質等級: 100
• 抗體產品種類: primary antibodies
• 無性繁殖: MI15, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: rat, ( Non-human primates), ( Human)
• 技術: flow cytometry: suitable
• 同型: IgG1κ
• UniProt登錄號: P18827
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SDC1(6382)

描述

一般說明

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

特異性

The mouse monoclonal antibody MI15 recognizes an extracellular epitope of CD138 (syndecan 1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes.

免疫原

A mixture of U266 and XG-1 human myeloma cell lines

外觀

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

準備報告

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

儲存和穩定性

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

其他說明

The antibody solution should be gently mixed before use.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable