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Merck
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重要文件

SAB4702004

Monoclonal Anti-NG2 PE produced in mouse

new

同義詞:

CSPG4, Chondroitin sulfate proteoglycan 4, MCSP, MSK16

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About This Item

分類程式碼代碼:
12352203

共軛

phycoerythrin (R-PE) conjugate

品質等級

抗體產品種類

primary antibodies

無性繁殖

7.1, monoclonal

形狀

buffered aqueous solution

物種活性

human

技術

flow cytometry: suitable

同型

IgG1

UniProt登錄號

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... CSPG4(1464)

一般說明

NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.

特異性

The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.

免疫原

Human bone marrow stromal cells infected with SV-40

外觀

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

準備報告

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

儲存和穩定性

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

其他說明

The antibody solution should be gently mixed before use.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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