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SAB4700552

Sigma-Aldrich

Monoclonal Anti-Cd3e antibody produced in hamster

clone 145-2C11, purified immunoglobulin, buffered aqueous solution

同義詞:

Anti-CD3

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

hamster

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

145-2C11, monoclonal

形狀

buffered aqueous solution

物種活性

mouse

濃度

1 mg/mL

技術

flow cytometry: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

mouse ... Cd3e(12501)

一般說明

The hamster monoclonal antibody 145-2C11 reacts with mouse CD3 (epsilon subunit). This antibody is commonly used as a phenotypic marker for mouse T cells.

免疫原

Mouse BM10-37 cytotoxic T lymphocytes

應用

The reagent is designed for Flow Cytometry analysis using 1-2 μg reagent / 1e6 cells in a suspension.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Susanne M A Lens et al.
Molecular and cellular biology, 22(15), 5419-5433 (2002-07-09)
The caspase 8 inhibitor c-FLIP(L) can act in vitro as a molecular switch between cell death and growth signals transmitted by the death receptor Fas (CD95). To elucidate its function in vivo, transgenic mice were generated that overexpress c-FLIP(L) in
Lisa A Pitcher et al.
European journal of immunology, 35(12), 3643-3654 (2005-11-01)
T cell receptor (TCR) signal transduction is mediated by the immunoreceptor tyrosine-based activation motifs (ITAM). The ten ITAM in the TCR complex are distributed in two distinct signaling modules termed TCR zetazeta and CD3 gammaepsilon/deltaepsilon. To delineate the specific role
Lingqiao Zhu et al.
Journal of immunology (Baltimore, Md. : 1950), 191(2), 737-744 (2013-06-19)
MHC class II-expressing thymocytes can efficiently mediate positive selection of CD4 T cells in mice. Thymocyte-selected CD4 (T-CD4) T cells have an innate-like phenotype similar to invariant NKT cells. To investigate the development and function of T-CD4 T cells in-depth
Qizhi Tang et al.
Journal of immunology (Baltimore, Md. : 1950), 168(9), 4480-4487 (2002-04-24)
FcR nonbinding anti-CD3 epsilon mAbs elicit partial TCR signaling that leads to T cell unresponsiveness and tolerance in vivo. In this study, the membrane-proximal events that promote T cell inactivation by FcR nonbinding anti-CD3 mAbs were examined. In the context
M Hanief Sofi et al.
Molecular immunology, 46(7), 1443-1450 (2009-02-03)
T helper (Th) cell differentiation is a key event to mount an appropriate immune response. Th1 and Th2 cells produce their signature cytokines IFN-gamma and IL-4, respectively. However, as we have reported, CD4 T cells selected by MHC class II-expressing

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