SAB4700088

Monoclonal Anti-CD8-PE antibody produced in mouse

clone MEM-31, purified immunoglobulin, buffered aqueous solution

• 分類程式碼代碼: 12352203
• NACRES: NA.44

屬性

• 生物源: mouse
• 共軛: phycoerythrin (R-PE) conjugate
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: MEM-31, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: flow cytometry: suitable
• 同型: IgG2a
• NCBI登錄號: NM_001145873.1
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CD8(925)

描述

一般說明

CD8 (cluster of differentiation 8), is a dimeric protein, encoded by the CD8A gene mapped to human chromosome 2p12. Human soluble CD8 (sCD8) is produced by activated CD8⁺ T lymphocytes.

免疫原

Crude thymus membrane fraction

應用

The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

生化／生理作用

CD8 (cluster of differentiation 8) acts as a vital co-receptor of cytotoxic T cells. Mutation in the gene has been associated with the development of respiratory infections. Soluble CD8 plays a major role in regulation of soluble human leucocyte antigen I (sHLA-I) mediated transfusion-related immunomodulation (TRIM). Elevated levels of sCD8 has been observed in polytransfused patients suffering from human immunodeficiency virus-negative haemophilia and β-thalassaemia major.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable