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SAB4504122

Sigma-Aldrich

抗-磷酸化-CaMK4 (pThr196/200) 兔抗

affinity isolated antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 51 kDa

物種活性

human, mouse, rat

濃度

~1 mg/mL

技術

ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pThr196/pThr200)

基因資訊

human ... CAMK4(814)

一般說明

Calcium/calmodulin-dependent protein kinase IV (CAMK4) is a multifunctional serine/threonine protein kinase. It is present in cells of the nervous and immune systems. This gene is located on human chromosome 5q22.

免疫原

The antiserum was produced against synthesized peptide derived from human CaMK4 around the phosphorylation site of Thr196/200.

Immunogen Range: 166-215

生化/生理作用

Calcium/calmodulin-dependent kinase 4 (CAMK4) controls blood pressure.This protein plays a major role in the spermatogenesis by phosphorylating protamines.. It controls vascular tone. Absence of CaMK4 gene promotes hypertension.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

CAMK4 gene variation is associated with hypertension in a Uygur population
Chen SZ, et al.
Genetics and molecular research : GMR, 15(1) (2016)
CaMK4 Gene Deletion Induces Hypertension
Santulli G
Journal of the American Heart Association (2012)
Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller
Racioppi L and Means AR
Trends in Immunology, 29(12), 600-607 (2008)
Akanksha Roy et al.
International journal of molecular sciences, 25(6) (2024-03-28)
Inherited retinal degenerative diseases (IRDs) are a group of rare diseases that lead to a progressive loss of photoreceptor cells and, ultimately, blindness. The overactivation of cGMP-dependent protein kinase G (PKG), one of the key effectors of cGMP-signaling, was previously
Genetic risk factors for the development of allergic disease identified by genome-wide association
Portelli MA, et al.
Clinical and Experimental Allergy, 45(1), 21-31 (2015)

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