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Merck
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重要文件

SAB4503695

Sigma-Aldrich

Anti-GASP1 antibody produced in rabbit

affinity isolated antibody

同義詞:

G-protein coupled receptor-associated sorting protein 1, GASP, GASP-1, GPRASP1, KIAA0443

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 156 kDa

物種活性

human

濃度

~1 mg/mL

技術

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBI登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... GASP1(9737)

一般說明

Anti-GASP1 Antibody detects endogenous levels of total GASP1 protein.
G-protein coupled receptor-associated sorting protein 1 (GASP-1) is expressed at high level in the olfactory bulb, hippocampus, hypothalamus and some thalamic and cortical regions. It is located on human chromosome Xq22. It is also termed as WFIKKNRP or WFIKKN2. GASP-1 has a whey acidic protein domain, a follistatin/Kazal domain, an Ig domain, two tandem Kunitz domains and a netrin domain.

免疫原

The antiserum was produced against synthesized peptide derived from human GASP1.

Immunogen Range: 741-790

生化/生理作用

G-protein coupled receptor-associated sorting protein 1 (GASP-1) acts as a ubiquitous tumor marker. It plays an important role in the post endocytic sorting process. It is also expected to play a major role in recycling and degradation of several G-protein-coupled receptors (GPCRs).

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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G-protein coupled receptor-associated sorting protein 1 (GASP-1), a ubiquitous tumor marker
Zheng X, et al.
Experiments in Microbial Genetics, 93(1), 111-115 (2012)
Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
Lee YS and Lee SJ
Proceedings of the National Academy of Sciences of the USA (2013)
A novel Xq22.1 deletion in a male with multiple congenital abnormalities and respiratory failure
Cao Y and Aypar U
European Journal of Medical Genetics, 59(5), 274-277 (2016)
Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1
Martini L, et al.
Faseb Journal, 21(3), 802-811 (2007)
Impaired striatum-dependent behavior in GASP-1-knock-out mice
Mathis C, et al.
Genes, Brain, and Behavior, 10(3), 299-308 (2011)

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