SAB4502725

Anti-CHP2 antibody produced in rabbit

affinity isolated antibody

• 同義詞: Calcineurin B homologous protein 2, Hepatocellular carcinoma-associated antigen 520
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 22 kDa
• 物種活性: rat, mouse, human
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI登錄號: O43745
• UniProt登錄號: O43745
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CHP2(63928)

描述

一般說明

Anti-CHP2 antibody detects endogenous levels of total CHP2 protein.

The CHP2 (calcineurin like EF-hand protein 2) gene is mapped to human chromosome 16p12.2. It encodes a 23kDa protein containing myristoylation site at its N-terminal and four EF-hand Ca²⁺ binding motifs. The gene is predominantly expressed in small intestine and cancer cells.

免疫原

The antiserum was produced against synthesized peptide derived from human CHP2.

Immunogen Range: 101-150

生化／生理作用

The protein encoded by CHP2 (calcineurin like EF-hand protein 2) gene serves as an important cofactor of Na⁺/H⁺ exchanger isoform 1 and maintains high intracellular pH in cancer cells. CHP2 protects cells from dying due to serum deprivation. Overexpression of the gene is observed in ovarian cancer and it is involved in the growth, proliferation, invasion and metastasis of cancer cells.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable