SAB4502201

Anti-PLAGL1 antibody produced in rabbit

affinity isolated antibody

• 同義詞: LOT-1, Lost on transformation 1, Pleiomorphic adenoma-like protein 1, Tumor supressor ZAC, Zinc finger protein PLAGL1
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 50 kDa
• 物種活性: human
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:10000; western blot: 1:500-1:1000
• NCBI登錄號: Q9UM63
• UniProt登錄號: Q9UM63
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... PLAGL1(5325)

描述

一般說明

The gene PLAGL1 (pleiomorphic adenoma-like protein 1), PLAGL2 and PLAG1 form a subfamily of PLAG family of zinc finger proteins that recognize DNA and RNA. The three members share similarity at the amino-terminal, but are functionally different, varying in their DNA binding capacities. The gene is mapped to human chromosome 6q24.2, a region implicated in several cancers.

免疫原

The antiserum was produced against synthesized peptide derived from human PLAGL1.

Immunogen Range: 311-360

生化／生理作用

The maternally-imprinted gene, PLAGL1 (pleiomorphic adenoma-like protein 1), functions as an oncogene as well as a tumor suppressor depending on the cell context. It has been found to exhibit anti-proliferative properties and regulate apoptosis and cell-cycle arrest via p53.

特點和優勢

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外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable