推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 52 kDa
物種活性
mouse, human
濃度
~1 mg/mL
技術
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... G3BP1(10146)
一般說明
Anti-G3BP-1 Antibody detects endogenous levels of total G3BP-1 protein.
G3BP1 (ras-GTPase-activating protein SH3 domain-binding protein 1) is a constituent of SGs (stress granules). It is located on human chromosome 5q14.2-5q33.3.
免疫原
The antiserum was produced against synthesized peptide derived from human G3BP-1.
Immunogen Range: 199-248
Immunogen Range: 199-248
生化/生理作用
G3BP1 (ras-GTPase-activating protein SH3 domain-binding protein 1) blocks the replication of HIV-1 (human immunodeficiency virus) in macrophages and T-cells. In gastric cancer patients, overexpression of G3BP1 leads to imperfect clinical predictions. It is required for the interactions of SG–PB (stress granule-processing bodies).
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Novel Role of Ras-GTPase Activating Protein SH3 Domain-Binding Protein G3BP in Adhesion and Migration of 32D Myeloid Progenitor Cells
The Open Hematology Journal, 6 (2012)
Overexpression of Ras-GTPase-activating protein SH3 domain-binding protein 1 correlates with poor prognosis in gastric cancer patients
Histopathology, 67(5), 677-688 (2015)
G3BP1 restricts HIV-1 replication in macrophages and T-cells by sequestering viral RNA
Virology, 486, 94-104 (2015)
G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA.
The Journal of Cell Biology, 209(1), 73-84 (2015)
Genes to cells : devoted to molecular & cellular mechanisms, 18(2), 135-146 (2013-01-03)
Upon exposure to various environmental stresses such as arsenite, hypoxia, and heat shock, cells inhibit their translation and apoptosis and then repair stress-induced alterations, such as DNA damage and the accumulation of misfolded proteins. These types of stresses induce the
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