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Merck
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重要文件

SAB4200806

Sigma-Aldrich

Anti-Ezrin antibody, Mouse monoclonal

clone 3C12, purified from hybridoma cell culture

同義詞:

Cytovillin, Villin-2, p81

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

抗體表格

purified from hybridoma cell culture

抗體產品種類

primary antibodies

無性繁殖

3C12, monoclonal

形狀

buffered aqueous solution

分子量

~80 kDa

物種活性

bovine, canine, hamster, kangaroo, human, monkey, rat, mouse

包裝

antibody small pack of 25 μL

濃度

~1 mg/mL

技術

immunoblotting: 1-2 μg/mL using using canine MDCK cells extract
immunofluorescence: 0.5-1  μg/mL using human epidermoid carcinoma A431 cells.

同型

IgG1

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

mouse ... Ezr(22350)

一般說明

Ezrin, also known as cytovillin, p81 or 80K, is a.member of the ERM proteins family composed of Ezrin, Radixin, and Moesin. These proteins are known as actin-binding proteins that link the cell membrane to the actin cytoskeleton, particularly in microvillus-bearing epithelial cells. Ezrin is present in microvilli, microspikes, and membrane ruffles of cells.
The ERM proteins family are involved in the functional expression of membrane proteins on the cell surface, integrate Rho guanosine 5′-triphosphatase (GTPase) signaling regulating cytoskeletal organization and act as protein kinase A (PKA)-anchoring proteins. Therefore, ERM proteins seem to play an important role in the membrane transport of electrolytes by ion channels and transporters.

免疫原

The carboxy-terminal part of recombinant human ezrin

應用

Monoclonal Anti-Ezrin recognizes an epitope located on the C-terminal region of Ezrin. Reactivity has been observed with human, mouse, hamster, monkey, bovine, canine, rat and rat-kangaroo origin. The antibody is recommended to use in various immunological techniques, including Immunoblotting (~80kDa), immunofluorescence, Immunohistochemistry and immunoprecipitation.

外觀

Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.

其他說明

This product is for R&D use only, not for drug, household, or other uses.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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