SAB4200270

Anti-PSMB9 antibody, Mouse monoclonal

clone LMP2-37, purified from hybridoma cell culture

• 同義詞: Monoclonal Anti-LMP2, Monoclonal Anti-PSMB6i, Monoclonal Anti-RING12, Monoclonal Anti-beta1i, Monoclonal Anti-proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
• 分類程式碼代碼: 12352203

屬性

• 生物源: mouse
• 共軛: unconjugated
• 抗體表格: purified from hybridoma cell culture
• 抗體產品種類: primary antibodies
• 無性繁殖: LMP2-37, monoclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 17 kDa
• 物種活性: human, mouse, rat
• 濃度: ~1.0 mg/mL
• 技術: immunocytochemistry: suitable; indirect ELISA: suitable; western blot: 1.0-2.0 μg/mL using extracts of rat spleen
• 同型: IgG2a
• UniProt登錄號: P28065
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... PSMB9(5698)

描述

一般說明

Monoclonal Anti-PSMB9 (mouse IgG2a isotype) is derived from the hybridoma LMP2-37 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human PSMB9 recombinant protein. Proteasome 20S subunit beta 9 (PSMB9) is present in the major histocompatibility complex (MHC) class II region. γ-interferon triggers the synthesis of three proteasomal subunits-PSMB9 (β1i), PSMB10 (β2i) and PSMB8 (β5i), which is a part of immunoproteasome.

免疫原

human PSMB9, recombinant protein.

應用

Monoclonal Anti-PSMB9 antibody produced in mouse has been used in:

• flow cytometry
• enzyme linked immunosorbent assay (ELISA)
• immunoblotting
• immunocytochemistry

生化／生理作用

Proteasome 20S subunit beta 9 (PSMB9) is used during antigen presentation. Aberrant levels of PSMB9 is involved in autoimmune disorders such as primary Sjogren′s syndrome and uterine leiomyosarcomas. The proteasome is a multicatalytic proteinase complex, which is involved in the regulation of essential cellular processes such as transcription, cell cycle progression, differentiation, apoptosis and in the control of stress and immune responses.

外觀

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable