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Merck
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重要文件

SAB4200233

Sigma-Aldrich

Anti-VIP36/ LMAN2 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

同義詞:

Anti-GP36B, glycoprotein GP36b, Anti-Lectin, mannose-binding 2, Anti-Vesicular integral protein of 36 kDa

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~36 kDa

物種活性

mouse, human, rat

濃度

~1.0 mg/mL

技術

western blot: 2.5-5.0 μg/mL using whole extracts of human HeLa or ACHN cells, rat Rat2 or mouse 3T3 cells.

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... LMAN2(10960)
mouse ... Lman2(66890)
rat ... Lman2(290994)

一般說明

Anti-VIP36/LMAN2 is produced in rabbit using as immunogen a synthetic peptide of human LMAN2 conjugated to KLH. VIP36 (vesicular-integral protein of 36 kDa) is a member of the leguminous-type (L-type) lectin family, which also includes ERGIC-53, ERGL and VIPL. L-type lectins are type I transmembrane proteins composed of a large luminal domain comprising a carbohydrate recognition domain (CRD) and a short cytosolic domain that mediates sorting within the early secretory pathway. VIP36 localizes mainly to the Golgi apparatus and cycles between the Golgi and the ER.

應用

Anti-VIP36/ LMAN2 antibody produced in rabbit has been used in immunoblotting.

生化/生理作用

Vesicular-integral protein of 36 kDa (VIP36) binds high mannose type glycoproteins in a Ca2+-dependent manner and may facilitate their sorting, trafficking and quality control.

外觀

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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存取文件庫

Role of the Lectin VIP36 in Post-ER Quality Control of Human alpha1-Antitrypsin
Reiterer V, et al.
Traffic, 11(8), 1044-1055 (2010)
Structural basis for recognition of high mannose type glycoproteins by mammalian transport lectin VIP36
Satoh T, et al.
Test, 282(38), 28246-28255 (2007)

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