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Merck
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重要文件

SAB4200231

Sigma-Aldrich

Anti-DCAL-1 antibody, Mouse monoclonal

clone UW50, purified from hybridoma cell culture

同義詞:

Anti-C-type lectin-like 1, Anti-CLECL1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

共軛

unconjugated

抗體表格

purified from hybridoma cell culture

抗體產品種類

primary antibodies

無性繁殖

UW50, monoclonal

形狀

buffered aqueous solution

物種活性

human

濃度

~1.0 mg/mL

技術

flow cytometry: 0.25-0.50 μg/test using 1x106 human Raji cells

同型

IgM

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CLECL1(160365)

一般說明

Dendritic cell-associated lectin-1 (DCAL-1), also known as C-type lectin-like-1 (CLECL1), is a novel C-type lectin-like molecule, encoded by the gene mapped to human chromosome 12p13.31. The encoded protein is exclusively expressed in human hematopoietic cells, in particular at high levels in dendritic cells (DCs) and B cells.
Monoclonal Anti-DCAL-1 (mouse IgM isotype) is derived from the hybridoma UW50 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice, immunized with a human DCAL-1 fusion protein

特異性

Monoclonal Anti-DCAL-1 recognizes human DCAL-1.

免疫原

human DCAL-1 fusion protein.

應用

Monoclonal Anti-DCAL-1 antibody produced in mouse may be used in flow cytometry.

生化/生理作用

Dendritic cell-associated lectin-1 (DCAL-1) functions as a T-cell co-stimulatory molecule and increases interleukin-4 secretion. The encoded protein is also implicated in the regulation of the immune response.

外觀

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

儲存和穩定性

For continuous use, store at 2-8°C for up to one month. For extended storage, freeze at -20°C in working aliquots. Repeated freezing and thawing,or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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存取文件庫

Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.
Ryan EJ
Journal of Immunology, 169, 5638-5648 (2002)
Elizabeth J Ryan et al.
Human immunology, 70(1), 1-5 (2008-11-26)
Dendritic cell-associated lectin-1 (DCAL-1), also known as C-type lectin-like-1 (CLECL1), is a novel C-type lectin-like molecule expressed by antigen presenting cells including dendritic cells (DCs). Here we report that incubation of immature DCs (iDCs) with an anti-DCAL-1 monoclonal antibody (mAb)

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