共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
TMOD1-A328, monoclonal
形狀
aqueous solution
分子量
antigen predicted mol wt 40.4 kDa
物種活性
human
技術
western blot: suitable
同型
IgG2b
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
基因資訊
human ... TMOD1(7111)
一般說明
Tropomodulin 1 (TMOD1) is an actin-capping protein, which is expressed in the cardiac muscle and in slow-twitch muscle fibers. It possesses two actin- and two tropomyosin (TM)-binding regions. The gene encoding this protein is localized on human chromosome 9q.
免疫原
TMOD1 purified recombinant protein
生化/生理作用
Tropomodulin 1 (TMOD1) prevents the elongation and depolymerization of actin filaments by binding to the slowly growing pointed end of the actin filament. It has been associated with triple-negative breast cancers (TNBC). TMOD1 may act as a stabilizer of β-catenin.
外觀
Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Tropomodulin 1 Expression Driven by NF-?B Enhances Breast Cancer Growth
Taku Ito-Kureha
Cancer Research, 75(1) (2015)
Complete trisomy 9 with unusual phenotypic associations: Dandy-Walker malformation, cleft lip and cleft palate, cardiovascular abnormalities
Gabriele Tonni, et.al
Taiwanese Journal of Obstetrics & Gynecology, 53(4), 592-597 (2014)
Leucine 135 of Tropomodulin-1 Regulates Its Association with Tropomyosin, Its Cellular Localization, and the Integrity of Sarcomeres*
Kimi Y and Larry Kedes
The Journal of Biological Chemistry (2006)
Mechanism of actin filament pointed end capping by tropomodulin
Jampani Nageswara Rao
Science, 345(6195), 463-467 (2014)
Complete trisomy 9 with unusual phenotypic associations: Dandy-Walker malformation, cleft lip and cleft palate, cardiovascular abnormalities
GabrieleTonni
Taiwanese Journal of Obstetrics & Gynecology, 53(4), 592-597 (2014)
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