共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
ADIPOQ-A277, monoclonal
形狀
aqueous solution
分子量
antigen predicted mol wt 24.9 kDa
物種活性
human
技術
western blot: suitable
同型
IgG1
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
基因資訊
human ... ADIPOQ(9370)
一般說明
Adiponectin (ADIPOQ) gene is mapped to human chromosome 3q27.3. The gene codes for a 244 amino acid protein with four distinct regions. ADIPOQ is secreted by the adipocytes and is a most abundant circulating hormone.
免疫原
ADIPOQ purified recombinant protein
生化/生理作用
Adiponectin (ADIPOQ) is an adipocyte specific secreted protein that circulates in the plasma. The protein has a C-terminal globular domain and an NH2-terminal collagen domain. It has anti-atherosclerotic and anti-inflammatory properties. ADIPOQ has a role in physiological processes such as energy homeostasis and obesity. It exhibits anti-diabetic action by interacting with adiponectin receptors, AdipoR1 and AdipoR2. Low levels of adiponectin are also linked with hypertension and dyslipidemia. Mutation in the gene encoding it is linked with risk for endometrial cancer.
外觀
Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
The Journal of Clinical Investigation, 116, 1784-1792 (2019)
Association Between Single Nucleotide Polymorphism +276G T (rs1501299) in ADIPOQ and Endometrial Cancer
Pathology Oncology Research, 22, 135-138 (2019)
Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients
Arteriosclerosis, Thrombosis, and Vascular Biology (2000)
Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians
Diabetes, 55, 375-384 (2019)
In silico Evaluation of Nonsynonymous Single Nucleotide Polymorphisms in the ADIPOQ Gene Associated with Diabetes, Obesity, and Inflammation
Avicenna Journal of Medical Biotechnology, 7(6), 121-121 (2015)
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