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SAB4100327

Sigma-Aldrich

Monoclonal Anti-ADIPOQ antibody produced in mouse

clone ADIPOQ-A277, culture supernatant

同義詞:

Anti-ACDC, Anti-ACRP30, Anti-ADIPQTL1, Anti-ADPN, Anti-APM-1, Anti-APM1, Anti-Adiponectin, C1Q and collagen domain containing, Anti-GBP28

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

ADIPOQ-A277, monoclonal

形狀

aqueous solution

分子量

antigen predicted mol wt 24.9 kDa

物種活性

human

技術

western blot: suitable

同型

IgG1

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... ADIPOQ(9370)

一般說明

Adiponectin (ADIPOQ) gene is mapped to human chromosome 3q27.3. The gene codes for a 244 amino acid protein with four distinct regions. ADIPOQ is secreted by the adipocytes and is a most abundant circulating hormone.

免疫原

ADIPOQ purified recombinant protein

生化/生理作用

Adiponectin (ADIPOQ) is an adipocyte specific secreted protein that circulates in the plasma. The protein has a C-terminal globular domain and an NH2-terminal collagen domain. It has anti-atherosclerotic and anti-inflammatory properties. ADIPOQ has a role in physiological processes such as energy homeostasis and obesity. It exhibits anti-diabetic action by interacting with adiponectin receptors, AdipoR1 and AdipoR2. Low levels of adiponectin are also linked with hypertension and dyslipidemia. Mutation in the gene encoding it is linked with risk for endometrial cancer.

外觀

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
Kadowaki T, et al.
The Journal of Clinical Investigation, 116, 1784-1792 (2019)
Association Between Single Nucleotide Polymorphism +276G T (rs1501299) in ADIPOQ and Endometrial Cancer
Bienkiewicz J, et al.
Pathology Oncology Research, 22, 135-138 (2019)
Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients
Hotta K, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology (2000)
Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians
Heid IM, et al.
Diabetes, 55, 375-384 (2019)
In silico Evaluation of Nonsynonymous Single Nucleotide Polymorphisms in the ADIPOQ Gene Associated with Diabetes, Obesity, and Inflammation
Swamy AN, et al.
Avicenna Journal of Medical Biotechnology, 7(6), 121-121 (2015)

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