推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human, mouse, rat
技術
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... DARC(2532)
一般說明
Duffy antigen/chemokine receptor (DARC) or atypical chemokine receptor 1 (ACKR1) is a membrane-bound protein. The gene encoding this chemokine receptor is localized on human chromosome 1q23.2.
免疫原
DARC antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human DARC.
生化／生理作用
Duffy antigen/chemokine receptor (DARC) or atypical chemokine receptor 1 (ACKR1) functions as an antigen of the Duffy (Fy) blood group system. It has a role in the infection of red blood cells (RBCs) by Plasmodium vivax and the lysis of RBCs by Staphylococcus aureus. The protein has been shown to be downregulated in colorectal cancer.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
聯結
The action of this antibody can be blocked using blocking peptide SBP3500242.
外觀
Supplied in PBS with 0.02% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到適合的產品？
試用我們的產品選擇工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Isabelle Bouyssou et al.
Cell host & microbe, 31(12), 2080-2092 (2023-12-07)
Vivax malaria has long been thought to be absent from sub-Saharan Africa owing to the high proportion of individuals lacking the Duffy antigen receptor for chemokines (DARC) in their erythrocytes. The interaction between P. vivax Duffy-binding protein (PvDBP) and DARC is
Population genetic analysis of the DARC locus (Duffy) reveals adaptation from standing variation associated with malaria resistance in humans.
McManus KF
PLoS Genetics (2017)
High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry?based blood group genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles
Stefan Meyer
Transfusion (2014)
Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes.
Spaan AN
Cell host & microbe (2015)
Expression of Duffy antigen receptor for chemokines (DARC) is down-regulated in colorectal cancer.
Zhou S
Journal of Receptor and Signal Transduction Research (2015)
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務