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SAB3500141

Sigma-Aldrich

Anti-TRESK antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-KCNK18, Anti-Potassium channel subfamily K member 18, Anti-TRESK2, Anti-TRIK

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human, rat, mouse

技術

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... KCNK18(338567)

一般說明

Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK is part of the potassium channel family. It is expressed in trigeminal and dorsal root ganglions. The protein is activated by calcium signals. The TRESK gene is localized on human chromosome 10q25.3.

免疫原

TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.

生化/生理作用

Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK contributes to background K+ currents in sensory neurons. Mutations in the gene encoding it have been associated with familial migraine with aura.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

聯結

The action of this antibody can be blocked using blocking peptide SBP3500141.

外觀

Supplied in PBS with 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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訂價

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Involvement of gap junction channels in the pathophysiology of migraine with aura
Denis Sarrouilhe
Frontiers in Physiology (2014)
Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel.
Bruner JK
European Journal of Pharmacology (2014)
KCNK18 (TRESK) genetic variants in Italian patients with migraine.
Rainero I
Headache (2014)
TRESK: the lone ranger of two-pore domain potassium channels.
Enyedi P
Molecular and Cellular Endocrinology (2012)

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