推薦產品
生物源
goat
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human
技術
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... IGF1(3479)
一般說明
Insulin-like growth factor 1 (IGF1) is a single polypeptide chain protein with three disulfide bridges. It is mainly produced by the liver and a wide range of extra-hepatic tissues. IGF1 is seen in normal and neoplastic breasts. The IGF1 gene is 84779 bp long and is made of 6 different exons. IGF-1 gene is located on human chromosome 12q23.2.
免疫原
Peptide with sequence RSVRAQRHTD, from the internal region of the protein sequence according to NP_001104753.1; NP_001104754.1; NP_001104755.1; NP_000609.1
應用
Anti-IGF1 antibody produced in goat has been used in western blotting.
生化／生理作用
Insulin-like growth factor 1 (IGF1) protein is essential for the development of children and adults. It plays a crucial role in general anabolic processes. IGF1 participates in differentiation and cell proliferation. It plays a key role in osteogenesis, muscle repair, and hypertrophy after trauma. IGF1 is also involved in the generation of axons in nerves and regeneration of a nerve after ischemic insult. It is known to participate in the clinical sequelae of Laron′s dwarfism. IGF1 is required for normal breast development.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
M Ouni et al.
The pharmacogenomics journal, 16(1), 102-106 (2015-04-15)
Short children using growth hormone (GH) to accelerate their growth respond to this treatment with a variable efficacy. The causes of this individual variability are multifactorial and could involve epigenetics. Quantifying the impact of epigenetic variation on response to treatments
IGF1 (Insulin-Like Growth Factor 1 (Somatomedin C))
Panayi ND and Burd R
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2013)
T L Wise
Genes, brain, and behavior, 16(2), 241-249 (2016-09-20)
Fragile X syndrome (FXS) is an inherited form of intellectual disability that is usually caused by expansion of a polymorphic CGG repeat in the 5' untranslated region of the X-linked FMR1 gene, which leads to hypermethylation and transcriptional silencing. Two
Marina Valente Barroso et al.
Bioorganic & medicinal chemistry, 25(20), 5557-5568 (2017-09-10)
Chronic obstructive pulmonary disease (COPD) is an incurable and progressive disease. Emphysema is the principal manifestation of COPD, and the main cause of this condition is cigarette smoke (CS). Natural products have shown antioxidant and anti-inflammatory properties that can prevent
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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