SAB1407182

Anti-EPB41L3 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

• 同義詞: 4.1B, DAL-1, DAL1, FLJ37633, KIAA0987
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~96.5 kDa
• 物種活性: human
• 技術: western blot: 1 μg/mL
• NCBI登錄號: BC006141.1
• UniProt登錄號: Q9Y2J2
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... EPB41L3(23136)

描述

一般說明

Erythrocyte membrane protein band 4.1-like 3 (EPB41L3)/protein 4.1B is expressed at high levels in the brain and neurons. Adipose tissue, kidney, testis, adrenal gland, and placenta also show high expression of EPB41L3. It is moderately expressed in the lungs and intestines. EPB41L3 gene is located on human chromosome 18p11.31. Protein 4.1B belongs to the protein 4.1 superfamily of proteins. It has an N-terminal 4.1/ezrin/radixin/moesin (FERM) domain.

免疫原

EPB41L3 (AAH06141.1, 1 a.a. ~ 865 a.a) full-length human protein.

Sequence
MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQTNLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKTDSERTDTAADGETTATEELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVPEEKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED

生化／生理作用

Erythrocyte membrane protein band 4.1-like 3 (EPB41L3)/protein 4.1B helps in linking cellular receptors with the cytoskeleton. It possesses tumor-suppressive action. In human, overexpression of EPB41L3 gene can stimulate apoptosis in breast cancer, non-small cell lung cancer, and meningioma cells.

外觀

Solution in phosphate buffered saline, pH 7.4

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable