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Merck
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重要文件

SAB1406878

Sigma-Aldrich

Anti-KIAA0101 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

同義詞:

PAF

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~12.32 kDa

物種活性

human

技術

immunofluorescence: suitable
western blot: 1 μg/mL

NCBI登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... KIAA0101(9768)

一般說明

KIAA0101, also known as, proliferating cell nuclear antigen (PCNA) clamp associated factor (PCLAF), is a proliferating cell nuclear antigen-associated factor. It is a 15kDa protein. It is highly expressed in thymus and colon. KIAA0101 gene is located on the human chromosome 15q22.31.

免疫原

KIAA0101 (NP_055551.1, 1 a.a. ~ 111 a.a) full-length human protein.

Sequence
MVRTKADSVPGTYRKVVAARAPRKVLGSSTSATNSTSVSSRKAENKYAGGNPVCVRPTPKWQKGIGEFFRLSPKDSEKENQIPEEAGSSGLGKAKRKACPLQPDHTNDEKE

生化/生理作用

KIAA0101, also known as, proliferating cell nuclear antigen (PCNA) clamp associated factor (PCLAF), helps in regulating DNA repair, cell cycle progression and cell proliferation. Overexpression of KIAA0101 inhibits UV-induced cell death. It is also used as a prognostic marker for hepatocellular carcinoma(HCC). Overexpression of KIAA0101 acts as a marker for adrenocortical carcinoma (ACC) and human gastric cancer.

外觀

Solution in phosphate buffered saline, pH 7.4

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals
Kulsk JK, et al.
Journal of Molecular Medicine, 83(12), 964-975 (2005)
KIAA0101 is overexpressed, and promotes growth and invasion in adrenal cancer
Jain M, et al.
PLoS ONE, 6(11), e26866-e26866 (2011)
Overexpression of KIAA0101 predicts high stage, early tumor recurrence, and poor prognosis of hepatocellular carcinoma
Yuan RH, et al.
Clinical Cancer Research, 13(18), 5368-5376 (2007)
Kun Zhu et al.
Cancer science, 104(3), 353-359 (2012-12-18)
Gastric cancer (GC) is one of the most common malignant tumors with a high rate of recurrence, which results in surgery being unsuccessful. Therefore, it is important to find the reason for the surgery failing. The purpose of the present

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