SAB1300728

Anti-Phospho-ANTXR1-pY382 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 同義詞: Anti-ANTXR1, Anti-ATR, Anti-Anthrax toxin receptor 1 [Precursor], Anti-TEM8, Anti-Tumor endothelial marker 8
• 分類程式碼代碼: 12352203
• NACRES: NA.43

屬性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: dot blot: suitable; indirect ELISA: 1:1000
• NCBI登錄號: NP_115584
• UniProt登錄號: Q9H6X2
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pTyr382)
• 基因資訊: human ... ANTXR1(84168)

描述

一般說明

ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.

免疫原

ANTXR1 (NP_115584, 363-396)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable