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Key Documents

SAB1300724

Sigma-Aldrich

Anti-Phospho-RASGRF1-S929 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

同義詞:

Anti-Guanine nucleotide-releasing protein, Anti-Ras-GRF1, Anti-Ras-specific guanine nucleotide-releasing factor 1, Guanine nucleotide-releasing factor 1, Ras-specific nucleotide exchange factor CDC25

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

技術

dot blot: suitable
indirect ELISA: 1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pSer929)

基因資訊

human ... RASGRF1(5923)

一般說明

RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.

免疫原

RASGRF1 (NP_002882, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S929 of human RASGRF1.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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