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S1315

SAFC

L-丝氨酸

同義詞:

(S)-2-氨基-3-羟基丙酸

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About This Item

線性公式:
HOCH2CH(NH2)CO2H
CAS號碼:
分子量::
105.09
Beilstein:
1721404
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209

生物源

non-animal source

化驗

≥98.5%

製造商/商標名

Ajinomoto

技術

cell culture | mammalian: suitable

雜質

endotoxin, tested

mp

222 °C (dec.) (lit.)

溶解度

H2O: 50 mg/mL

適合性

suitable for manufacturing use

應用

pharmaceutical (small molecule)

SMILES 字串

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI 密鑰

MTCFGRXMJLQNBG-REOHCLBHSA-N

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一般說明

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

應用

L-Serine is classified as a non-essential amino acid. It is used as a cell culture media component and raw material for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

生化/生理作用

通过丝氨酸羟甲基转移酶获得甘氨酸时的前体。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Miyoshi Haruta et al.
Science (New York, N.Y.), 343(6169), 408-411 (2014-01-25)
Plant cells are immobile; thus, plant growth and development depend on cell expansion rather than cell migration. The molecular mechanism by which the plasma membrane initiates changes in the cell expansion rate remains elusive. We found that a secreted peptide
Kenji Hashimoto et al.
Progress in neuro-psychopharmacology & biological psychiatry, 29(5), 767-769 (2005-06-09)
Several lines of evidence suggest that D-serine, an endogenous agonist of the glycine site on the NMDA receptors, might play a role in the pathophysiology of schizophrenia. The purpose of this study was to determine whether levels of D- and
Vanessa A Morais et al.
Science (New York, N.Y.), 344(6180), 203-207 (2014-03-22)
Under resting conditions, Pink1 knockout cells and cells derived from patients with PINK1 mutations display a loss of mitochondrial complex I reductive activity, causing a decrease in the mitochondrial membrane potential. Analyzing the phosphoproteome of complex I in liver and
Chang-Ching Liu et al.
Molecular and cellular biology, 34(1), 57-70 (2013-10-30)
In budding yeast (Saccharomyces cerevisiae), the cell cycle-dependent telomere elongation by telomerase is controlled by the cyclin-dependent kinase 1 (Cdk1). The telomere length homeostasis is balanced between telomerase-unextendable and telomerase-extendable states that both require Cdc13. The recruitment of telomerase complex
Cedric Cagliero et al.
Nucleic acids research, 41(12), 6058-6071 (2013-05-02)
To fit within the confines of the cell, bacterial chromosomes are highly condensed into a structure called the nucleoid. Despite the high degree of compaction in the nucleoid, the genome remains accessible to essential biological processes, such as replication and

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