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S0508

Sigma-Aldrich

磺胺间甲氧嘧啶

同義詞:

4-氨基-N-(6-甲氧基-4-嘧啶基)苯磺酰胺, 4-甲氧基-6-磺胺嘧啶, N1-(6-甲氧基-4-嘧啶基)磺胺, SMM

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About This Item

經驗公式(希爾表示法):
C11H12N4O3S
CAS號碼:
分子量::
280.30
Beilstein:
621128
MDL號碼:
分類程式碼代碼:
51283946
PubChem物質ID:
NACRES:
NA.85

形狀

powder

品質等級

顏色

white to yellow-white

溶解度

methanol: soluble 10 mg/mL

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria
parasites

作用方式

DNA synthesis | interferes
enzyme | inhibits

SMILES 字串

COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1

InChI

1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)

InChI 密鑰

WMPXPUYPYQKQCX-UHFFFAOYSA-N

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一般說明

化学结构:磺胺

應用

磺胺间甲氧嘧啶可用于研究Fe3O4磁性纳米颗粒介导的降解。 可用于血液动力学研究支气管炎鲍特氏菌(Bordetella bronchiseptica)的荚膜形成

生化/生理作用

磺胺间甲氧嘧啶是二氢喋呤合成酶的竞争性抑制剂,用于阻断叶酸的合成。

其他說明

保存于密闭容器内,置于干燥通风处。

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


分析證明 (COA)

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C Girardi et al.
Pharmacological research, 22(2), 79-86 (1990-03-01)
Intrauterine administration was performed in six Friesan cows with a disposable spray preparation containing 3 g of sulfamonomethoxine and 3 g of oxytetracycline, in order to investigate their serum kinetics. Sulfamonomethoxine levels were determined by a reversed-phase HPLC method, whilst
Thomas Trolle et al.
Bioinformatics (Oxford, England), 31(13), 2174-2181 (2015-02-27)
Numerous in silico methods predicting peptide binding to major histocompatibility complex (MHC) class I molecules have been developed over the last decades. However, the multitude of available prediction tools makes it non-trivial for the end-user to select which tool to
A Kuwano
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 38(9), 685-688 (1991-11-01)
Bordetella bronchiseptica phase I organism possesses a capsule and has the ability to agglutinate with K antiserum, although phase III organism lacks both. The present study examines the effect of sulfamonomethoxine (SMMX) on capsule formation of B. bronchiseptica. I also
Hiromi Ito et al.
Carbohydrate research, 338(16), 1621-1639 (2003-07-23)
Systematic synthesis and myelin-associated glycoprotein (MAG)-binding activity of novel sulfated GM1b analogues structurally related to Chol-1 (alpha-series) gangliosides, high-affinity ligands for neural siglecs, are described. The suitably protected gangliotriose derivatives, 2-(trimethylsilyl)ethyl 2-acetamido-2-deoxy-6-O-levulinoyl-beta-D-galactopyranosyl-(1-->4)-2,3,6-tri-O-benzyl-beta-D-galactopyranosyl-(1-->4)-2,3,6-tri-O-benzyl-beta-D-glucopyranoside and 2-(trimethylsilyl)ethyl 2-acetamido-2-deoxy-6-O-levulinoyl-beta-D-galactopyranosyl-(1-->4)-2,6-di-O-benzyl-3-O-levulinoyl-beta-D-galactopyranosyl-(1-->4)-2,3,6-tri-O-benzyl-beta-D-glucopyranoside were each glycosylated with alpha-NeuAc-(2-->3)-galactose
Jingchun Yan et al.
Journal of hazardous materials, 186(2-3), 1398-1404 (2011-01-18)
Iron oxide magnetic nanoparticles (Fe(3)O(4) MNPs) can effectively activate persulfate anions (S(2)O(8)(2-)) to produce sulfate free radicals (SO(4)(-)), which are a powerful oxidant with promising applications to degrade organic contaminants. The kinetics of sulfamonomethoxine (SMM) degradation was studied in the

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