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Merck
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Q110

Sigma-Aldrich

Quinelorane dihydrochloride

crystalline

同義詞:

(5aR-trans)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride, LY-163,502

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About This Item

經驗公式(希爾表示法):
C14H22N4 · 2HCl
CAS號碼:
分子量::
319.27
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

形狀

crystalline

顏色

white

溶解度

H2O: >10 mg/mL

SMILES 字串

Cl.Cl.[H][C@]12CCCN(CCC)[C@]1([H])Cc3cnc(N)nc3C2

InChI

1S/C14H22N4.2ClH/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12;;/h9-10,13H,2-8H2,1H3,(H2,15,16,17);2*1H/t10-,13-;;/m1../s1

InChI 密鑰

WDEMLQIGYYLRRX-OWVUFADGSA-N

基因資訊

human ... DRD2(1813)

生化/生理作用

D2 dopamine receptor agonist; 2-aminopyridine analog of quinpirole.

法律資訊

Manufactured and sold with the permission of Eli Lilly and Company.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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M J Eaton et al.
The Journal of pharmacology and experimental therapeutics, 268(2), 645-652 (1994-02-01)
The purpose of the present study was to characterize dopaminergic D2 receptor-mediated regulation of catecholaminergic neurons in the diencephalon by examining the acute effects of the potent and selective D2 agonist quinelorane (LY163502; trans-(-)-5,5a,6,7,8,9,9a,10-octahydro-6-propylpyrimido [4,5-g] quinolin-2-amine dihydrochloride dihydrate) on concentrations
M A Charles et al.
Pharmacology, biochemistry, and behavior, 43(4), 1087-1092 (1992-12-01)
LY163502, a selective D2 receptor agonist, has been reported to stimulate sexual behavior in both copulating and noncopulating male rats. Three experiments were conducted to further characterize the role of dopamine on male sexual behavior. In the first experiment, quinelorane
J H Carlson et al.
Synapse (New York, N.Y.), 11(3), 229-248 (1992-07-01)
The rates and patterns of discharge activity exhibited by 16 spontaneously active substantia nigra pars compacta dopamine neurons were studied in halothane-anesthetized rats using three types of quantitative measures: 1) mean discharge rates, 2) population characteristics of interspike interval samples

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