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PRS3905

Sigma-Aldrich

Anti-TRPC3 (ab3) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-Short transient receptor potential channel 3, Anti-Transient receptor potential cation channel, subfamily C, member 3

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse, human

技術

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TRPC3(7222)

一般說明

TRPC3 (transient receptor potential-canonical 3) belongs to TRPC family. It is present in sperm. It is located on chromosome 4q27.

免疫原

a 14 amino acid peptide from near the carboxy-terminus of human TRPC3.

應用

Anti-TRPC3 has been used in immunofluorescent staining.

生化/生理作用

TRPC3 (transient receptor potential-canonical 3) participates in motility and capacitation of sperm. It is responsible for the proliferation of ovarian cancer cell in vitro and in vivo.

聯結

The action of this antibody can be blocked using blocking peptide SBP3905.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

FSH enhances the proliferation of ovarian cancer cells by activating transient receptor potential channel C3
Tao X, et al.
Endocrine-Related Cancer, 20(3), 415-429 (2013)
Transient receptor potential-canonical 3 modulates sperm motility and capacitation-associated protein tyrosine phosphorylation via [Ca2+]i mobilization
Ru Y, et al.
Acta biochimica et biophysica Sinica, 47(6), 404-413 (2015)
TRP channels in endothelial function and dysfunction
Kwan HY, et al.
Biochimica et Biophysica Acta, 1772(8), 907-914 (2007)
Yanfei Ru et al.
Acta biochimica et biophysica Sinica, 47(6), 404-413 (2015-04-26)
Ca(2+) signaling is pivotal for sperm maturation, including the processes of motility, capacitation, and the acrosome reaction. As a Ca(2+) conductor, transient receptor potential-canonical 3 (TRPC3) plays an important role in somatic cells. However, the function of TRPC3 in sperm

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