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PLA0253

Sigma-Aldrich

Rabbit anti-NPM1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

同義詞:

B23, NPM, member 1, nucleolar phosphoprotein B23, nucleolar protein NO38, nucleophosmin/nucleoplasmin family, numatrin, testicular tissue protein Li 128

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
暫時無法取得訂價和供貨情況

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

等級

Powered by Bethyl Laboratories, Inc.

物種活性

human

技術

immunoprecipitation (IP): 5-10 μg/mg

登錄號

NP_002511.1

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

rabbit ... NPM1(4869)

免疫原

The epitope recognized by PLA0253 maps to a region between residue 200 and 250 of human nucleophosmin using the numbering given in entry NP_002511.1 (GeneID 4869).

外觀

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

其他說明

Nucleophosmin (NPM1) is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. It associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. NPM1 binds ribosomes presumably to drive ribosome nuclear export. Chromosomal aberrations involving NPM1 have been identified in several types of leukemia [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P06748].

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Da Shi et al.
Scientific reports, 7, 39700-39700 (2017-01-04)
Porcine epidemic diarrhea virus (PEDV) replicates in the cytoplasm of infected cells, but its nucleocapsid (N) protein localizes specifically to the nucleolus. The mechanism of nuclear translocation, and whether N protein associates with particular nucleolar components, is unknown. In this

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