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Key Documents

PLA0003

Sigma-Aldrich

Rabbit anti-Phospho BRCA1 (S1280) Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

同義詞:

BRCA1/BRCA2-containing complex, BRCAI, BRCC1, BROVCA1, FANCS, Fanconi anemia, IRIS, PNCA4, PPP1R53, PSCP, RING finger protein 53, RNF53, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, complementation group S, early onset, early onset breast cancer 1, protein phosphatase 1, regulatory subunit 53, subunit 1, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

等級

Powered by Bethyl Laboratories, Inc.

物種活性

human

技術

immunoprecipitation (IP): 2.5 μg/mg
western blot: 1:1,000- 1:10,000

登錄號

NP_009225.1

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

human ... BRCA1(672)

免疫原

Immunogen for PLA0003 was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1280 according to the numbering given in entry NP_009225.1.

外觀

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

其他說明

BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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