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Merck
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P9357

Sigma-Aldrich

Anti-Potassium Channel Kv1.5 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

同義詞:

Anti-ATFB7, Anti-HCK1, Anti-HK2, Anti-HPCN1, Anti-KV1.5, Anti-PCN1

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

mouse, rat

技術

western blot (chemiluminescent): 1:200-1:400

UniProt登錄號

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

mouse ... Kcna5(16493)
rat ... Kcna5(25470)

相關類別

一般說明

Pivotal role of potassium channel is maintaining cell volume, membrane potential and neuronal excitability. Two families of potassium channel exists- one with inwardly rectifying potassium channel and the other with voltage sensing (KV) big conductance, calcium activated (BKCA ) small conductance and calcium activated (SK) potassium channel. KV1.5 channel is O2 sensitive, so hypoxia inhibits the expression of KV1.5 channel through 15-HETE pathway. Anti-Potassium Channel Kv1.5 antibody reacts specifically with full length Kv1.5 protein of rat and mouse.

免疫原

GST fusion protein from the C-terminal of mouse potassium channel Kv1.5 corresponding to amino acids 513-602.

應用

Anti-Potassium Channel Kv1.5 antibody can be used in immunocytochemistry, immunoblotting and immunofluorescence.

外觀

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.05% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Xiaojie Chu et al.
Prostaglandins & other lipid mediators, 88(1-2), 42-50 (2008-11-06)
Hypoxia initiated pulmonary vasoconstriction is due to the inhibition of voltage-gated K(+) (K(V)) channels. But the mechanism is unclear. We have evidence that hypoxia activates 15-lipoxygenase (15-LOX) in distal pulmonary arteries and increases the formation of 15-hydroxyeicosatetraenoate (15-HETE). 15-HETE-induced pulmonary
Gloria Juliana Rey-Parra et al.
American journal of respiratory and critical care medicine, 178(4), 399-406 (2008-05-31)
Neonatal chronic lung disease (CLD), caused by prolonged mechanical ventilation (MV) with O(2)-rich gas, is the most common cause of long-term hospitalization and recurrent respiratory illness in extremely premature infants. Recurrent episodes of hypoxemia and associated ventilator adjustments often lead

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