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P6847

Sigma-Aldrich

Monoclonal Anti-Interleukin-2−R-Phycoerythrin antibody produced in mouse

clone 5334, purified immunoglobulin, buffered aqueous solution

同義詞:

Monoclonal Anti-IL-2

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About This Item

分類程式碼代碼:
51111800
NACRES:
NA.41

生物源

mouse

品質等級

共軛

phycoerythrin (R-PE) conjugate

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

5334, monoclonal

形狀

buffered aqueous solution

物種活性

human

技術

flow cytometry: suitable

同型

IgG1

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... IL2(3558)

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一般說明

Interleukin-2 (IL-2) also refers as T Cell Growth Factor is a cytokine produced by certain subsets of T lymphocytes. It plays various functions like inducing interferon γ and B cell growth factor secretion as well as affecting the activation and proliferation of NK cells. It also has a vital role in modulating the expression of the IL-2 receptor and can facilitate B cell growth and differentiation. Mouse monoclonal anti-Interleukin-2−R-Phycoerythrin antibody reacts specifically with human IL-2.

特異性

The conjugates will identify and quantitate cells containing intracellular forms of human IL-2 by flow cytometry.

免疫原

recombinant human IL-2

應用

Monoclonal anti-Interleukin-2−R-Phycoerythrin antibody can be used in flow cytometry assays for identifying intracytoplasmic cytokines and for enumerating cytokine producing cells present in a mixed population.

外觀

Solution in buffered saline containing 0.5% bovine serum albumin and 0.1% sodium azide.

準備報告

Purified antibody is conjugated to R-phycoerythrin (PE).

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Selective in vivo growth of T lymphocytes from normal human bone marrows.
Morgan DA
Science, 193(4257), 1007-1008 (1967)
T A Waldmann et al.
The Journal of experimental medicine, 160(5), 1450-1466 (1984-11-01)
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2. Resting normal B cells and unselected B cell lines established from normal individuals were Tac antigen negative.
K A Smith et al.
Proceedings of the National Academy of Sciences of the United States of America, 82(3), 864-868 (1985-02-01)
The cell surface density of high-affinity membrane receptors for the T-lymphocytotrophic hormone interleukin 2 (IL-2) determines the rate of T-cell-cycle progression. Since 10-fold greater numbers of IL-2 receptor molecules were found by using a radiolabeled monoclonal antibody reactive with IL-2

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