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Merck
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重要文件

P5988

Sigma-Aldrich

PA28 Activator from rabbit

≥95% (SDS-PAGE), buffered aqueous solution

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About This Item

MDL號碼:
分類程式碼代碼:
12352202

品質等級

化驗

≥95% (SDS-PAGE)

形狀

buffered aqueous solution

分子量

170 kDa

運輸包裝

dry ice

儲存溫度

−70°C

一般說明

Manufactured for Sigma by Boston Biochem., Inc.

生化/生理作用

Protein activator of the 20S proteasome. Enhances the 20S proteasome hydrolysis of peptide substrates, but not hydrolysis of ubiquitinated proteins.

外觀

Solution in 50 mM Hepes, pH 7.6, 250 mM NaCl, 1 mM EDTA, and 1 mM DTT.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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W Dubiel et al.
The Journal of biological chemistry, 267(31), 22369-22377 (1992-11-05)
We have identified and purified a protein complex from human red blood cells that activates the multicatalytic protease (MCP). The complex, which we call the regulator, sediments at 11 S and is composed of 30-kDa subunits. The regulator does not
M Chu-Ping et al.
Biochimica et biophysica acta, 1119(3), 303-311 (1992-03-12)
An inhibitory protein for the 20S proteasome (also known as macropain, the multicatalytic proteinase complex and 20S proteinase) has been purified from bovine red blood cells. The inhibitor has an apparent molecular weight of 31,000 on SDS-PAGE and appears to

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