跳轉至內容
Merck
全部照片(1)

文件

P5396

Sigma-Aldrich

磷霉素 二钠盐

antibacterial MurA inhibitor

同義詞:

(-)-(1R,2S)-(1,2-环氧丙基)膦酸, Fosfomycin, Phosphonomycin

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C3H5Na2O4P
分子量::
182.02
Beilstein:
4604425
EC號碼:
MDL號碼:
分類程式碼代碼:
51102829
PubChem物質ID:
NACRES:
NA.85

品質等級

形狀

powder

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

作用方式

cell wall synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

[Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O

InChI

1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1

InChI 密鑰

QZIQJIKUVJMTDG-JSTPYPERSA-L

尋找類似的產品? 前往 產品比較指南

相關類別

應用

Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine.

生化/生理作用

聚集在肾脏和膀胱中的抗生素;降低含铂抗肿瘤制剂的肾毒性和耳毒性。磷霉素可以抑制 UDP-GlcNAc 烯醇式丙酮酸转移酶 (MurA)(细菌细胞壁生物合成中的酶)。

其他說明

1g,5g,50g
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

A L Barry et al.
Antimicrobial agents and chemotherapy, 35(6), 1235-1238 (1991-06-01)
Fosfomycin tromethamine (previously fosfomycin trometamol) is an orally administered fosfomycin which may be used for single-dose therapy of uncomplicated urinary tract infections. Fosfomycin tromethamine, norfloxacin, and trimethoprim-sulfamethoxazole inhibited greater than 90% of 352 bacterial isolates representing 25 different species; trimethoprim
Andrea Endimiani et al.
Antimicrobial agents and chemotherapy, 54(1), 526-529 (2009-11-11)
In vitro activity of fosfomycin was evaluated against 68 bla(KPC)-possessing Klebsiella pneumoniae (KpKPC) isolates, including 23 tigecycline- and/or colistin-nonsusceptible strains. By agar dilution, 93% of the overall KpKPC were susceptible (MIC(50/90) of 16/64 microg/ml, respectively). The subgroup of 23 tigecycline-
Nikos Fatsis-Kavalopoulos et al.
PLoS biology, 18(9), e3000856-e3000856 (2020-09-18)
Antibiotic combination therapies are important for the efficient treatment of many types of infections, including those caused by antibiotic-resistant pathogens. Combination treatment strategies are typically used under the assumption that synergies are conserved across species and strains, even though recent
Avigail Stokar-Avihail et al.
Cell host & microbe, 25(5), 746-755 (2019-05-10)
Temperate phages can adopt either a lytic or lysogenic lifestyle within their host bacteria. It was recently shown that Bacillus-subtilis-infecting phages of the SPbeta group utilize a peptide-based communication system called arbitrium to coordinate the lysogeny decision. The occurrence of peptide-based

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務