化驗
≥98% (HPLC)
形狀
powder
顏色
white
溶解度
DMSO: ~23 mg/mL
H2O: insoluble
儲存溫度
2-8°C
SMILES 字串
Cl.C1CCC(CC1)\N=C(/NC23CC4CC(CC(C4)C2)C3)N5CCOCC5
基因資訊
human ... KCNJ8(3764)
生化／生理作用
Selective inhibitor of Kir6.1/SUR2B channels.
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
H Kovalev et al.
British journal of pharmacology, 141(5), 867-873 (2004-02-06)
1. In this study, we have used Kir6.1/Kir6.2 chimeric proteins and current recordings to investigate the molecular basis of PNU-37883A inhibition of cloned K(ATP) channels. 2. Rat Kir6.1, Kir6.2 and Kir6.1/Kir6.2 chimeras were co-expressed with either SUR2B or SUR1, following
Bobby D Nossaman et al.
Journal of cardiovascular pharmacology, 50(4), 358-366 (2007-12-01)
The free radical peroxynitrite (ONOO-) is formed in biological systems from the reaction of nitric oxide (NO) with superoxide (O2-) and can react with protein and nonprotein thiol groups to produce tissue injury. However, these pathologic actions of (ONOO-) may
Mariko Yamanaka et al.
International immunopharmacology, 2(13-14), 1957-1964 (2002-12-20)
It is suggested that attenuation of the renal kallikrein-kinin system (KKS) involved the development of hypertension in young spontaneously hypertensive rats (SHR). In the present study, a comparison was made between young SHR and Wistar Kyoto rats (WKY) to examine
Salma Toma Hanna et al.
European journal of pharmacology, 515(1-3), 34-42 (2005-05-17)
Kir6.1 subunit is one of the pore-forming components of K(ATP) channel complex. The endogenous modulation of Kir6.1 subunit function has been largely unknown. Whether acetylcholine modulated the function of Kir6.1 subunit stably expressed in human embryonic kidney (HEK-293) cells was
Noriyoshi Teramoto et al.
European journal of pharmacology, 506(1), 1-7 (2004-12-14)
Kinetic studies of U-37883A (4-morpholinecarboximidine-N-1-adamantyl-N'-cyclohexyl-hydrochloride), a vascular ATP-sensitive K+ channel (KATP channel) blocker, were performed on pig urethral myocytes to investigate inhibitory effects on large-conductance intracellular Ca2+ -sensitive K+ channels (i.e., BKCa channels; 225 pS K+ channels) by use of
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務