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P0119

Sigma-Aldrich

Anti-Purinergic Receptor P2Y14 (extracellular) 兔抗

affinity isolated antibody, lyophilized powder

同義詞:

Anti-GPR105, Anti-P2YR14

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

human, rat

技術

western blot: 1:200 using rat brain and lung lysates, and rat heart membranes

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

免疫原

peptide CIELKSELGRKWHKASN corresponding to residues 172-188 of human P2Y14 extracellular loop.

標靶描述

P2Y14 belongs to the P2Y receptor family that is part of the G-protein coupled receptor superfamily. P2Y14 is expressed in several tissues including brain, lung, and several cells of hematopoietic origin such as T lymphocytes and dendritic cells. This receptor is apparently involved in chemotaxis, maturation of immature dendritic cells, and neuroimmune regulation.

外觀

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

重構

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Jennifer Patritti Cram et al.
eLife, 11 (2022-03-22)
Neurofibromatosis type 1 (NF1) is characterized by nerve tumors called neurofibromas, in which Schwann cells (SCs) show deregulated RAS signaling. NF1 is also implicated in regulation of cAMP. We identified the G-protein-coupled receptor (GPCR) P2ry14 in human neurofibromas, neurofibroma-derived SC

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