跳轉至內容
Merck
全部照片(1)

重要文件

P0031

Sigma-Aldrich

原人参二醇

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C30H52O3
CAS號碼:
分子量::
460.73
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.25

形狀

powder

顏色

white

溶解度

methanol: 5 mg/mL, clear, colorless

儲存溫度

2-8°C

SMILES 字串

C[C@@]12CC[C@@]3([H])C(C)(C)[C@@H](O)CC[C@]3(C)[C@@]1([H])C[C@@H](O)[C@@]4([H])[C@]2(CC[C@]4([H])[C@@](CCC=C(C)C)(C)O)C

InChI

1S/C30H52O3/c1-19(2)10-9-14-30(8,33)20-11-16-29(7)25(20)21(31)18-23-27(5)15-13-24(32)26(3,4)22(27)12-17-28(23,29)6/h10,20-25,31-33H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24-,25-,27-,28+,29+,30-/m0/s1

InChI 密鑰

PYXFVCFISTUSOO-HKUCOEKDSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

人参皂苷代谢物已通过糖皮质激素受体 (GR) 和雌激素受体(ER) 与内皮细胞功能相关。

應用

可将一种达玛烷型四环萜烯皂苷元——丹普烷型二醇[20(R-protopanaxadiol)用于研究其通过糖皮质激素 (GR) 和雌激素 (ER) 受体与内皮细胞功能的结合和调节。原托那沙二醇可用于研究细胞色素P450的分解代谢。与20 (S)-原花粉二醇相比,20 (R)-原花粉二醇可用于比较研究。

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Gang Zhen et al.
Science China. Life sciences, 58(11), 1099-1110 (2015-11-14)
Panax ginseng C. A. Meyer is an important traditional herb in eastern Asia. It contains ginsenosides, which are primary bioactive compounds with medicinal properties. Although ginseng has been cultivated since at least the Ming dynasty to increase production, cultivated ginseng
Alain Gulenga Musende et al.
Anti-cancer drugs, 23(5), 543-552 (2012-04-07)
This study focuses on determining the pharmacokinetics, biodistribution, and efficacy of the ginsenoside aglycone protopanaxadiol (aPPD) administered as a single agent in a novel oral dosage formulation. To obtain these data and to characterize the stability of aPPD, appropriate analytical
Liang Li et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(3), 472-483 (2010-12-09)
20(S)-Protopanaxadiol (PPD, 1) is one of the aglycones of the ginsenosides and has a wide range of pharmacological activities. At present, PPD has progressed to early clinical trials as an antidepressant. In this study, its fate in mixed human liver
Xin Jin et al.
Fitoterapia, 84, 64-71 (2012-09-26)
As with many other anti-cancer agents, 20(S)-protopanaxadiol (PPD) has a low oral absorption. In this study, in order to improve the oral bioavailability of PPD, the cubic nanoparticles that it contains were used to enhance absorption. Therefore, the cubic nanoparticle
Hai-jian Xia et al.
International journal of nanomedicine, 8, 545-554 (2013-02-23)
Mixed micelles are widely used to increase solubility and bioavailability of poorly soluble drugs. One promising antitumor drug candidate is 20(S)-protopanaxadiol (PPD), although its clinical application is limited by low water solubility and poor bioavailability after oral administration. In this

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務