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Merck
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重要文件

O9505

Sigma-Aldrich

Orotidine

≥90% (HPLC)

同義詞:

Uridine-6-carboxylic acid

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About This Item

經驗公式(希爾表示法):
C10H12N2O8
CAS號碼:
分子量::
288.21
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:

化驗

≥90% (HPLC)

形狀

powder

溶解度

water: 50 mg/mL, clear, colorless to light yellow

儲存溫度

−20°C

SMILES 字串

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C(=O)NC(=O)C=C2C(O)=O

InChI

1S/C10H12N2O8/c13-2-4-6(15)7(16)8(20-4)12-3(9(17)18)1-5(14)11-10(12)19/h1,4,6-8,13,15-16H,2H2,(H,17,18)(H,11,14,19)/t4-,6-,7-,8-/m1/s1

InChI 密鑰

FKCRAVPPBFWEJD-XVFCMESISA-N

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應用

Orotidine, a nucleoside found naturally in fungi, bacteria and plants, may be used as a reference for the determination of presence of orotidine in urine or plasma due to urea cycle-related (transamidation) metabolic deficiencies or diseases.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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H Horiuchi et al.
Life sciences, 66(21), 2051-2070 (2000-05-24)
We investigated the relationship between the toxic effect of allopurinol and pyrimidine metabolism in mice. Allopurinol-induced increases in plasma transaminase levels in dinitrofluorobenzene (DNFB)-sensitized mice were not affected by uridine. In contrast, plasma creatinine and BUN tended to decrease 18
A B Burlina et al.
Journal of inherited metabolic disease, 15(5), 707-712 (1992-01-01)
The allopurinol challenge test was performed on 44 healthy subjects (28 children and 16 adolescents) in order to establish normal values of urinary orotic acid excretion following allopurinol ingestion in the paediatric population. The subjects were divided into three groups
Elizabeth M Brown et al.
PloS one, 8(3), e59237-e59237 (2013-03-28)
Analysis of the population genetic structure of microbial species is of fundamental importance to many scientific disciplines because it can identify cryptic species, reveal reproductive mode, and elucidate processes that contribute to pathogen evolution. Here, we examined the population genetic
E R Hauser et al.
The New England journal of medicine, 322(23), 1641-1645 (1990-06-07)
Ornithine carbamoyltransferase is an X-linked mitochondrial enzyme expressed in hepatocytes and enterocytes. A deficiency of this enzyme results in central nervous system dysfunction, which may be fatal in newborn boys. Milder forms are seen in older boys and girls and
The allopurinol loading test in detecting obligate heterozygotes for OCT deficiency.
I Sebesta et al.
Journal of inherited metabolic disease, 17(1), 133-134 (1994-01-01)

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