NCSTUD002

MISSION^® Synthetic microRNA Inhibitor

cel-miR-243-3p, Negative Control 2, Sequence from Caenorhabditis elegans with no homology to human and mouse gene sequences

• 同義詞: Synthetic Tough Decoy, sTuD
• 分類程式碼代碼: 41105324
• NACRES: NA.51

屬性

• 產品線: MISSION^®
• 形狀: solid
• 成熟序列: CGGUACGAUCGCGGCGGGAUAUC
• Sanger 成體/幼體登錄號: MIMAT0000299
• Sanger microRNA登錄號: MI0000319
• 儲存溫度: −20°C

描述

一般說明

Individual synthetic microRNA inhibitors were designed using a proprietary algorithm, which is based on the work of Haraguchi, T, et al. and in collaboration with Dr. Hideo Iba, University of Tokyo.† This algorithm utilizes the tough decoy (TuD) design. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation.

The MISSION synthetic miRNA Inhibitors are small, double-stranded RNA molecules designed to inhibit a specific mature miRNA. The miRNA inhibitors were designed using the mature miRNA sequence information from miRBase and are 2′-O-methylated RNA duplexes with a miRNA binding site on each strand. Optimal miRNA inhibition is provided after transfection due to the robust secondary structure of the inhibitor.

• Long lasting inhibition at very low dosage
• Excellent resistance to cellular nucleases
• Custom synthesis available for a variety of species

其他說明

Based on miRBase V19

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H373
• 防範說明: P260 - P314 - P501
• 危險分類: STOT RE 2 Inhalation
• 標靶器官: Respiratory Tract
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable