N6909

Neurturin human

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

• 同義詞: NRTN, NTN
• MDL號碼: MFCD01867712
• 分類程式碼代碼: 51111800

屬性

• 生物源: human
• 重組細胞: expressed in E. coli
• 化驗: >95% (SDS-PAGE)
• 形狀: lyophilized powder
• 效力: 15-50 ng/mL ED₅₀
• 分子量: monomer calculated mol wt ~12.5 kDa; predicted mol wt ~14 kDa by SDS-PAGE (reducing)
• 儲存條件: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• 雜質: endotoxin, tested
• UniProt登錄號: Q99748
• 儲存溫度: −20°C
• 基因資訊: human ... NRTN(4902)

描述

生化／生理作用

Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways.

Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways. Human and mouse NTN share 91% sequence identity.

外觀

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg bovine serum albumin.

分析報告

The biological activity is measured by its ability to bind recombinant human GFRα2/Fc.

安全資訊

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)